Use of BRIX-3000 Enzymatic Gel in Mechanical Chemical Removal of Caries: Clinical Case Report

Autores

  • Klissia Romero Felizardo Paranaense University, Faculty of Dentistry. PR. Brazil http://orcid.org/0000-0001-8083-3077
  • Nayara Priscila de Alvarenga Barradas Paranaense University, Faculty of Dentistry. PR. Brazil.
  • Gabriella Fernanda Guedes Paranaense University, Faculty of Dentistry. PR. Brazil.
  • Fernanda da Conceição Antônio Ferreira Unopar, Faculty of Dentistry. PR, Brasil.
  • Murilo Baena Lopes Unopar, Faculty of Dentistry. PR, Brasil. http://orcid.org/0000-0001-6198-7695

DOI:

https://doi.org/10.17921/2447-8938.2018v20n2p87-93

Resumo

Abstract

Less traumatic alternative methods for removal of decayed tissue has been developed. A non-invasive technique, which consists of applying a proteolytic substance that softens the infected dentin tissue and preserves healthy tooth tissue was released in the market. Thus, this work intended to describe a clinical case of caries removal using BRIX 3000 papaine-based enzymatic gel. A 6-year-old male patient attend to a Univesity Dental Clinic complaining of painful sensitivity during mastication. After examination, acute deep carious lesion was found in dental elements 64 and 65. The caries removal procedure was performed for both teeth without anesthesia, under relative isolation, following the principles of atraumatic restorative treatment - ART. The gel was taken into the cavity and leaved to act for 2 minutes and the infected tissue was excavated. Caries lesion was then detected below the OM cusp with undercut enamel, needing to enlarge the cavity in the occlusal region with rotating cutting instruments and reapply the gel. After the second application, all the infected tissue had been removed and the teeth restoration with chemical ionomer cement was performed. At the end of the treatment, the discomfort during the performed procedure was asked to the patient using the Wong-Baker Face Scale. The child pointed to score 1, indicating mild pain for both treatments. It can be concluded that the use of enzymatic papaine gel-based was an efficient alternative for caries removal, easy to use, and preserve to the maximum the dental structure healthy, showing promise to be used as atraumatic caries removal technique.

Keywords: Dental Caries. Papain. Pediatric Dentistry.

Resumo

Métodos alternativos menos traumáticos para remoção de cárie vem sendo desenvolvidos. Uma técnica não invasiva, que consite na aplicação de uma substância proteolítica que amolece a dentina infectada e preserva o tecido dental hígido foi lançado no mercado. Sendo assim, este trabalho visa relatar um caso clínico de remoção da lesão de cárie através do gel enzimático a base de papaína, BRIX-3000. Paciente do gênero masculino, 6 anos, compareceu à Clínica Odontológica Universitária com queixa de sensibilidade dolorosa durante a mastigação. Após avaliação, constatou-se lesão cariosa profunda aguda nos elementos dentais 64 e 65. O procedimento de remoção de cárie foi realizado sem anestesia e sob isolamento relativo, seguindo os princípios do tratamento restaurador atraumático (ART). O gel foi levado à cavidade, deixado agir por 2 minutos e realizado a escavação do tecido infectado. Foi detectado lesão de cárie abaixo da cúspide OM com esmalte socavado, necessitando de ampliação da cavidade na região oclusal com instrumentos cortantes rotatórios e reaplicação do gel. Após a segunda aplicação, todo o tecido infectado foi removido e realizada a restauração dos dentes com cimento de ionômero químico. Ao final do tratamento, foi aplicado a escala de faces de Wong-Baker. A criança apontou score 1, indicando dor leve para ambos os tratamentos. Pôde se concluir que a utilização do gel enzimático a base de papaína é uma alternativa eficiente para remoção do tecido cariado, de fácil utilização, preservando ao máximo a estrutura dental sadia, sendo promissor para ser utilizado na técnica atraumática de remoção da cárie.

Palavras-chave: Cárie Dentária. Papaína. Odontopediatria.

Biografia do Autor

Klissia Romero Felizardo, Paranaense University, Faculty of Dentistry. PR. Brazil

Professor Titular, Faculdade de Odontologia

Nayara Priscila de Alvarenga Barradas, Paranaense University, Faculty of Dentistry. PR. Brazil.

Aluno de graduação, Faculdade de Odontologia

Gabriella Fernanda Guedes, Paranaense University, Faculty of Dentistry. PR. Brazil.

Aluno de graduação, Faculdade de Odontologia

Fernanda da Conceição Antônio Ferreira, Unopar, Faculty of Dentistry. PR, Brasil.

Aluno de mestrado, Programa de pós graduação stricto sensu em Odontologia

Murilo Baena Lopes, Unopar, Faculty of Dentistry. PR, Brasil.

Professor Titular, Programa de pós graduação stricto sensu em Odontologia

Referências

Jingarwar MM, Bajwa NK, Pathak A. Minimal intervention Dentistry - A new frontier in clinical Dentistry. J Clin Diagnostic Res 2014;8(7):4-8. doi:10.7860/JCDR/2014/9128.4583

Mackenzie L, Banerjee A. Minimally invasive direct restorations: A practical guide. Br Dent J 2017;223(3):163-171. doi:10.1038/sj.bdj.2017.661

Dhamija N, Pundir P. A Review on Agents for Chemo-mechanical Caries Removal. Sch J Dent Sci J Dent Sci 2016;3(9):264-268. doi:10.21276/sjds.2016.3.9.5

Brennan DS, Balasubramanian M, Spencer AJ. Treatment of caries in relation to lesion severity: Implications for minimum intervention dentistry. J Dent 2015;43(1):58-65. doi:10.1016/j.jdent.2014.10.009.

Ammari MM, Moliterno LFM, Hirata Júnior R, Séllos MC, Soviero VM, Coutinho Filho WP. Efficacy of chemomechanical caries removal in reducing cariogenic microbiota: a randomized clinical trial. Braz Oral Res 2014;28(1):1-6. doi:10.1590/1807-3107BOR-2014.vol28.0031

Hamama H, Yiu C, Burrow M. Current update of chemomechanical caries removal methods. Aust Dent J 2014;59(4):446-456. doi:10.1111/adj.12214

Divya G, Prasad MG, Vasa AAK, Vasanthi D, Ramanarayanar B, Mynampati P. Evaluation of the efficacy of caries removal using Polymer Bur, Stainless Steel Bur, Carisolv, Papacarie – An invitro comparative study. J Clin Diagnostic Res 2015;9(7):ZC42-ZC46. doi:10.7860/JCDR/2015/12705.6202.

Schutzbank SG, Marchwinski M, Kronman JH, Goldman M, Clark RE. In Vitro Study of the Effect of GK-101 on the Removal of Carious Material. J Dent Res 1975;54(4):907. doi:10.1177/00220345750540043801.

Schutzbank SG, Galaini J, Kronman JH, Goldman M, Clark RE. A comparative in vitro study of GK-101 and GK-101E in caries removal. J Dent Res 1978;57(9-10):861-4. doi:10.1177/00220345780570090201.

Scheutzel P. Possibilities and limitations of Caridex System as an alternative to conventional caries removal. Dtsch Zahnarztl Z 1989;44(8):612-4.

Roth KK, Domnick E, Ahrens G. Studies into the effectivity of Caridex in caries removal. Dtsch Zahnarztl Z 1989;44(6):463-5.

Lai G, Capi CL, Cocco F, Cagetti MG, Lingström P, Almhöjd U, et al. Comparison of Carisolv system vs traditional rotating instruments for caries removal in the primary dentition: A systematic review and meta-analysis. Acta Odontol Scand 2015;73(8):569-80. doi:10.3109/00016357.2015.1023353.

Pradeep Kumar R. A natural chemo-mechanical caries removal agent- Papacarie. Int J Pharma Bio Sci 2014;5(4):P394-P399. doi:10.17354/cr/2015/33

Kittu J, Anshul BS, Geetha AG. Papacarie: a chemomechanical caries removal agent. IJSS Case Reports Rev 2015;1(9):57-60. doi:10.17354/cr/2015/33.

Abdul Khalek A, Elkateb M, Abdel Aziz W, El Tantawi M. Effect of papacarie and alternative restorative treatment on pain reaction during caries removal among children: a randomized controlled clinical trial. J Clin Pediatr Dent 2017;41(3):219-224. doi:10.17796/1053-4628-41.3.219

Frencken JE, Songpaisan Y, Phantumvanit P, Pilot T. An atraumatic restorative treatment (ART) technique: evaluation after one year. Int Dent J 1994;44(5):460-464. http://www.ncbi.nlm.nih.gov/pubmed/7814116.

Holmgren CJ, Roux D, Doméjean S. Minimal intervention dentistry: Part 5. Atraumatic restorative treatment (ART)-a minimum intervention and minimally invasive approach for the management of dental caries. Br Dent J 2013;214(1):11-18. doi:10.1038/sj.bdj.2012.1175

Wong D, Baker C. Pain in children: comparison of assessment scales. Pediatr Nurs 1988;14(1):9-17.

Dorri M, Sheiham A, Marinho Valeria CC. Atraumatic restorative treatment versus conventional restorative treatment for the management of dental caries. Cochrane Database Syst Rev 2009;(4). doi:10.1002/14651858.CD008072

Jawa D, Singh S, Somani R, Jaidka S, Sirkar K, Jaidka R. Comparative evaluation of the efficacy of chemomechanical caries removal agent (Papacarie) and conventional method of caries removal: an in vitro study. J Indian Soc Pedod Prev Dent 2010;28(2):73-77. doi:10.4103/0970-4388.66739.

Kamdar RS, Pradeep S. Chemomechanical agents used in caries excavation. Res J Pharm Technol 2016;9(10):1765-1767. doi:10.5958/0974-360X.2016.00355.3

Schwendicke F. Retracted: modern concepts for caries tissue removal. J Esthet Restor Dent 2016:n/a-n/a. doi:10.1111/jerd.12201

Ricketts D, Lamont T, Innes NPT, Kidd E, Clarkson JE. 12 - Operative caries management in adults and children. Cochrane database Syst Rev 2013;3:CD003808. doi:10.1002/14651858.CD003808.pub3

Tyas MJ, Anusavice KJ, Frencken JE, Mount GJ. Minimal intervention dentistry - A review: FDI Commission Project 1-97. Int Dent J 2000;50(1):1-12. doi:10.1111/j.1875-595X.2000.tb00540.x

Kochhar GK, Srivastava N, Pandit IK, Gugnani N, Gupta M. An evaluation of different caries removal techniques in primary teeth: a comparitive clinical study. J Clin Pediatr Dent 2011;36(1):5-9. http://www.ncbi.nlm.nih.gov/pubmed/22900437.

Martins MD, Fernandes KPS, Pavesi VC, França CM, Mesquita-Ferrari RA, Bussadori SK. Healing properties of papain-based gel on oral ulcers. Brazilian J Oral Sci 2011;10(2):120-3.

Maragakis GM, Hahn P, Hellwig E. Chemomechanical caries removal: A comprehensive review of the literature. Int Dent J 2001;51(4):291-9. doi:10.1002/j.1875-595X.2001.tb00841.x

Banerjee A, Watson TF, Kidd EA. Dentine caries excavation: a review of current clinical techniques. Br Dent J 2000;188(9):476-82. doi:10.1038/sj.bdj.4800515a

Torresi F, Bsereni L. Eficácia do método de remoção químico-mecânica da cárie dentária como papaína em adultos. Rev Assoc Paul Cir Dent 2017;71(3):266-9.

Tomlinson D, von Baeyer CL, Stinson JN, Sung L. A Systematic Review of Faces Scales for the Self-report of Pain Intensity in Children. Pediatrics 2010;126(5):e1168-e1198. doi:10.1542/peds.2010-1609

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Publicado

2018-06-30

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1.
Felizardo KR, Barradas NP de A, Guedes GF, Ferreira F da CA, Lopes MB. Use of BRIX-3000 Enzymatic Gel in Mechanical Chemical Removal of Caries: Clinical Case Report. J. Health Sci. [Internet]. 30º de junho de 2018 [citado 26º de abril de 2024];20(2):87-93. Disponível em: https://journalhealthscience.pgsscogna.com.br/JHealthSci/article/view/6040

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